DPCstruct | MC22825

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)243 ± 30 aa
Standard deviation of domain lengths30.08
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score83.76
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)19.30
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W1V1H0 302-553 ATGASSAPMLRRVWGLIGFTTNSQLVTFLSKANGLTIAANKIWILAKLILPDVIIKAAPSRGTANVFETTFHELAHASHFRQVGSGY…
A0A4Q8QGU5 32-279 KFYALVHNAAYDFYDRAVRKFGIHHPNQSWLRISARYYGELADSRHNDLNINGGFAWVPLLGWKSEIQVGRLSQGKYEGSDKIYGIV…
A0A2T7BMA1 316-586 None
A0A661YYY1 6-247 None
A0A661Z462 314-586 None
B0MZ52 5-238 None
A0A7M4D5B0 2-214 None
A0A7V3X8I6 162-430 None
A0A1V5YN41 367-579 None
A0A521AD85 24-226 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.