DPCstruct | MC22810

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)158 ± 33 aa
Standard deviation of domain lengths33.08
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score71.68
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)29.64
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A524PS40 46-192 KVPRETILQLDEEAVAEEDETGEMPEEPLPGFDTSLLDLDYSVQDWLTATPEPVREPEKKSEAELVNSFLASNPRIGPVKELTEGTS…
A0A090W060 8-134 THSFNEWLKLTRLKPIKRPEDLDEKDSDPKVNSLTSNASENTTHFEIIDKFIAENPKITPSKTNAPKGNLAKVRTAQPEALMTETLA…
A0A840EQ66 121-266 None
A0A7Z0G785 543-691 None
A0A223P1Q7 418-653 None
A0A7C1DZD2 92-234 None
A0A3E1NJG0 328-556 None
A0A0U3K149 72-286 None
A0A0M3C9Q4 26-224 None
A0A380C2F2 181-377 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.