DPCstruct | MC22800

Metacluster Properties and Pfam Annotations

Number of structural domains61
Mean domain length (aa)406 ± 106 aa
Standard deviation of domain lengths105.97
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score71.22
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)21.08
Pfam Score77.82
Assigned Pfam label(s) PF01253- PF21023- CL0668

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A550CGA3 96-469 ISGRWAPNLTRRRPRWLRRGGRRSGRRGHLFPVSSNAFYTAHVLPCRPAFPDLVLPPSGDPSNAGPRDISIKTSTHKSLVAFLKAAE…
A0A7J7SQK5 2-248 QQEQIIQVKELSKGVESIVAVDWKHPRITSFVIPEPSPTSQTIQEGSREQPYHPPDIKPLYCVPASMSLLFQESGHKKGSILEGGEV…
A0A4U5M3T2 28-337 None
A0A0F7SGV7 356-839 None
A0A812MBX7 88-536 None
A0A139Y3U7 14-280 None
A0A0F4Z0C3 63-647 None
A0A4C1ZU97 33-561 None
A0A4R0RAQ1 451-944 None
A0A1Q8S3B1 1-217 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.