DPCstruct | MC22779

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)98 ± 7 aa
Standard deviation of domain lengths7.06
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score87.54
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)28.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A174TX13 7-109 QNAGDDFFLNQRGAKVFYDESRQPLLPIAKGKNVYKVLSIGFGNTGTPMVTIESGRETVCYKLPYEYSEWAMTVVECANMGEKLVPG…
A0A3D5ZLZ5 99-190 DYTRQGYLDIPKLKSNKERGAIYQVLSVGFFGGNEQPCVTIYKDEQAQCLLLPKELSDWAFDMVAFSNIGGNFFPSDVEFGYINGRY…
A0A2X4YHW2 219-316 None
A0A243BMC8 17-124 None
A0A1A0JRH7 4-93 None
A0A1S2NTP5 29-126 None
A0A285GFY1 2-90 None
A0A2C1BQ66 7-99 None
A0A353YX98 10-119 None
A0A1L5LKE3 407-505 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.