DPCstruct | MC22777

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)113 ± 10 aa
Standard deviation of domain lengths10.43
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score89.94
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)31.22
Pfam Score100.00
Assigned Pfam label(s) CL0264

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7K3KZE4 1-104 MAQRTFSVFGDSISTFEGVTSPANRIYYAGDLRRSTGVLEPEDTWWARVIAHFDGRLVSNAAFSGSMVDGAGFPAGHTPERIAEIAG…
A0A373KZR9 21-131 EETEDGIRVSFFGDSITTYKDYSGTQGYYYDESMLPVESTWWMRLLGEEQWILGVNESIGGTRVTWDGVTEDEKQFIGNEWYLGLEE…
A0A3D3YK17 960-1072 None
A0A1Q9JCQ8 66-180 None
A0A810PYU0 295-416 None
A0A1G9EUD0 17-125 None
A0A7X7BZ97 67-171 None
A0A6I2NIH9 945-1044 None
R5FTI5 641-737 None
A0A354UPF0 898-1017 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.