DPCstruct | MC22772

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)166 ± 25 aa
Standard deviation of domain lengths25.06
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score77.66
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)18.88
Pfam Score100.00
Assigned Pfam label(s) PF17231

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A645EQ34 2-147 ALPLPKNPTLFELQKPEPVQRFGVITEMEESRLPPSFELLAAFGAMGAAGIALILFARLFTRRLTPQEEERTAREKLKRKYGGRMIR…
A0A6J6NP79 2-134 RRVIRPTLTGSIPTTIRNHISIARYAFPVLHLRLLGIALLAAAGFLAIFHGKLRRDNALHPIEERVAAHLGLVVVPVDALALPAGAA…
A0A7M1UUN6 186-346 None
V4XZY2 42-233 None
U1NV93 255-375 None
A0A2B7GXL0 1-155 None
R5YJH0 18-188 None
A0A0N8PR89 122-306 None
A0A2H5YHV4 311-473 None
F1TA67 175-339 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.