DPCstruct | MC22770

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)232 ± 19 aa
Standard deviation of domain lengths19.14
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score90.79
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)24.35
Pfam Score100.00
Assigned Pfam label(s) PF01955

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A645EMA0 80-279 EYVYIPGTINIILHISAALTPGAMTRALITCTEAKTAALQELLAPSCYSSGIATGSGTDGCIIVSDLTSPVKLTDAGKHNKLGELIG…
A0A7X2P6Z5 211-447 GTINIILMVNQRMTDAAMLRALVLCSEAKAAAVQELLLGSCYSHEIATGSGTDGTIIAAPMESEYLLTTASGHVKLGELIGKTVKKA…
A0A3R6YJE9 3-233 None
H1D501 1-234 None
A0A0U1L404 151-390 None
A0A7C5U9B1 88-368 None
A0A843DVK3 26-256 None
A0A1E7IFL7 149-373 None
A0A7C5RLA4 120-355 None
A0A843CZB0 1-211 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.