DPCstruct | MC2276

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)120 ± 11 aa
Standard deviation of domain lengths11.49
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score89.51
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)26.78
Pfam Score100.00
Assigned Pfam label(s) PF21746

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R6UP56 22-139 DFVAAYVRSLYAASVAERFDTQDSWASDAVTLIAFDDPQKLISIVLRVLDTDPPDEILPVLAAGPLEDYLCHCGIDAIENLERLVEN…
A0A6M8BLB2 2-122 KSNEIQHWAQTYIEAQKRQITNTEDPLWWAIDLFFELMESKPEACWEVLLEISRRNPPEGVISIAGAGPLEDLIDSHGNRFIDQIEV…
A0A4Z0BPB7 79-182 None
A0A1H4A4H6 3-112 None
A0A2E2QLS9 110-225 None
B9XLL4 14-125 None
A0A5C7XK07 7-147 None
A0A256WWW2 69-172 None
A0A1E5XXI3 157-284 None
A0A1E3W7Z7 121-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.