DPCstruct | MC22757

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)69 ± 2 aa
Standard deviation of domain lengths1.52
Length coefficient of variation0.02
Mean AlphaFold2 pLDDT confidence score91.66
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)45.19
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J4XE98 3-69 SISIDLETRSSVDIGKSGVYRYAEAEDFAILLFGYSVDGGTVQVIDLVGGEQIPQEILDALTDECII
W4UCU7 1-70 MRQIAIDIETFSPAPLAKTGVYPYAEHPDFRLLIFGYSIDGGPVEVVDLASGGGLPDEVLAALVDPGVVK
A0A1G5G9L2 1-70 None
B3WYJ2 1-72 None
A0A1H3XAV6 1-70 None
A0A249DX47 1-69 None
A0A174FHK7 21-87 None
A0A6I2J080 8-74 None
A0A6I1MQ40 1-70 None
A0A345CZ15 8-75 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.