DPCstruct | MC22744

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)223 ± 30 aa
Standard deviation of domain lengths29.86
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score81.83
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)23.62
Pfam Score90.00
Assigned Pfam label(s) PF16989- PF06812

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0H3JFF5 3-162 QPSAPAPQIAIDSHDDKAWRDTLLKVAAILCERQPDSPQGYRLRRHALWQSITSTPQAESDGRTPLAAVSADMVADYQSRLASADMA…
A0A2X4WJF9 1-210 MQGFVPRLKNRLARSGGMEALVPQNSSTQEHGREAAHSDSPQLSAVKSGRDLLDQAKLLSRWLSEQPQGWLASHRLIKTVRWDTVDQ…
A0A2V9ZJL9 247-434 None
A0A824EST3 16-240 None
A0A368E590 252-448 None
A0A447XA48 376-627 None
A0A447X861 16-237 None
A0A3C0PDM3 125-345 None
A0A8A8CHL5 136-370 None
A0A444J4E6 38-219 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.