DPCstruct | MC22738

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)53 ± 4 aa
Standard deviation of domain lengths3.75
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score94.38
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.92
Mean intra-cluster sequence similarity (%)72.76
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I1IQB6 55-108 RNLLEAGLLHNDVTTVAGKGLQHYTKEPKLIDGKLTWVDGVVQSLDDKVLRSID
A0A2X4T8K0 1-54 MRELLNAGLLHEDVNTVAGFGLKRYTLEPWLNNGELDWREGAERSLDNDVIASF
A0A0H3GRZ4 1-54 None
A0A376FAR3 22-70 None
A0A5S9I7R0 6-62 None
A0A378AA27 225-278 None
A0A6N6XDK9 19-72 None
A0A2X3EF00 30-83 None
A0A3S4KT10 26-68 None
A0A2X3H9S6 50-106 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.