DPCstruct | MC22728

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)191 ± 37 aa
Standard deviation of domain lengths36.86
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score74.69
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)50.89
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5K4EW16 224-432 GTVINQPVVILRDPAALEQEKLEREEQERRKALQLYVFVMRCIAYPFYSKPPTDLIRRYLKITKQQLNTFKERFQAFLSGELDVVGD…
A0A401PK29 26-201 TQVEKVVKKAYGMLAFIGRGIEYKNWQLNKQQLQVVKERFQAFLNGETQIVADEAFWNAIQSYYESFLKSDRVARMVHSGGCSANDF…
A0A183MT02 23-183 None
A0A5K4F7R2 258-480 None
A0A183J6C6 23-187 None
A0A183LFJ6 192-427 None
A0A819NB31 182-414 None
A0A1Y1NF41 91-319 None
K1P853 1-271 None
S9XDD7 29-182 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.