DPCstruct | MC22727

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)124 ± 8 aa
Standard deviation of domain lengths7.80
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score86.45
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)49.40
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C9A498 58-178 YMTGKLLLKLDTVNFIISNHTREHFPFLEEHRCSRSRTTFYYTIGWLIFMEDSHVKFKSSMEPLLKVFIALESTPDAMFRTDTVKYS…
A0A4D9F2H7 1-128 MDGKNTHSVRQYAVKFMLQNHTSKHFPFLGVNDNYSLSDLRCRTTFYTALTRLLMVDLGEDEDEFENFMLPLTVSFETVTQIFNNSF…
A0A453ERI8 1-133 None
F7B593 303-415 None
A0A401STW4 1-111 None
A0A453ERD9 263-379 None
A0A0S7KL32 106-232 None
A0A4S2MC79 552-686 None
A0A6P5QKX4 623-751 None
A0A6I9XIM8 458-584 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.