DPCstruct | MC22722

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)128 ± 7 aa
Standard deviation of domain lengths6.99
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score84.02
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)60.03
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3SBN3 1-129 MKRGMKALRQLREKSKKRGVDDVESDRSDPSSFDHALSHLQQSLAHLDTLGHAFVLSLKDSNQERLQSYSRTYDLSRSERSKVQALA…
A0A7J8FK49 177-306 RMAIKAVKHFIEKSRKRNLEENIQEANGSEMTYVDALNHLEKSLAHLETLNHSFIVSLKNSEQEILQKYCKLYDLSRSESGKLRDQA…
Q9D3Z9 3-132 None
A0A5C6NPW2 129-254 None
A0A444UPB0 6-115 None
A0A822F1Z9 80-203 None
A0A2I0TQ90 595-735 None
A0A834A8M7 218-346 None
A0A834A3N7 1134-1264 None
A0A7J8E3I3 3-131 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.