DPCstruct | MC22721

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)216 ± 18 aa
Standard deviation of domain lengths18.42
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score80.07
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)37.09
Pfam Score100.00
Assigned Pfam label(s) PF10486

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q0IHV3 1-243 MEHSEAEVDMIHQKVRAILRGLDGQHPALQSDHGMLRWTLHKSLDRNPASGSVIVGILIKELEKAERSDTLHYIIPLLHTLMYTITK…
A0A1S3S3S5 1-214 PPFLLKGEVKRVYLSYIVCLSECFAGLCINRWSLEELVKRDPRNFIILLQQILRKTREVLEQSQDELVVPLALLFSSTLLQTPHFSP…
A0A2K6P314 1-239 None
S7Q3M4 4-186 None
A0A6P9AYE9 1-215 None
A0A4Z2B1H4 8-220 None
L9JV47 26-256 None
S4R547 1-221 None
A0A6G0J8B6 11-216 None
A0A6A4T5S7 1-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.