DPCstruct | MC2272

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)60 ± 5 aa
Standard deviation of domain lengths5.38
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score83.79
Mean fraction of residues predicted as intrinsically disordered0.14
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)53.56
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6V7Q3J3 78-131 MLAIVCKTYEGVKALEKHDNEGMIDTNAGLYGLGPPIGRLLNGRFLVLCLEKLS
A0A5P1ER57 134-196 SRLLSEFLGLETMLAIVCKTYEGVKALERYDKEGMIDKSSGLHGLGLSIGRLVDGRFRVICLE
A0A843UG44 526-594 None
A0A6A2YC28 1-52 None
A0A6V7PY51 79-127 None
A0A4Y7J9Q8 696-754 None
A0A6A2Y0N8 1-54 None
A0A5P1F3N4 215-274 None
A0A067K094 20-83 None
A0A7J0ECF5 1-52 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.