DPCstruct | MC22719

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)219 ± 20 aa
Standard deviation of domain lengths20.24
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score78.42
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)33.98
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J7QZJ8 64-255 ADVQPVLDMFTHQNPRDHETWETRYMLLLWLSVACLIPFDFSRLDGNLVTQPGQTRVSIMDRILQIAESYLVVSDKARDAAAVLVSK…
A0A1S3S0C3 1-245 TWETRYMLLLWLSMTCLIPFDLSRLDGHLTSDPSQTREPIMDRILAIAKSYLMVSDKSRDAASVLVSKFVTRPDVKLKRLGDFLDWS…
A0A1I8FH57 329-573 None
M7AHE1 638-861 None
A0A452YM90 148-348 None
A0A158Q3E8 155-375 None
L1J4H8 93-285 None
A0A1I7ZMN7 1-232 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.