DPCstruct | MC22704

Metacluster Properties and Pfam Annotations

Number of structural domains74
Mean domain length (aa)159 ± 30 aa
Standard deviation of domain lengths29.88
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score77.36
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)36.08
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3DMM5 1-103 MTDLKGKEVKRSTLNELVEYITNGRGVLTEPVYPEIIKMISVNLFRTLPPSENPDFDPEEDDPTLEAAWPHLTLVYELFLRFLESSD…
A0A820B934 25-177 RLQESSRLGQKNFRPELEALPLLKETSADQQEKLFVAKLKQCCVIFDFSDCVSDLKSKEIKRACLNEIVDYITVTRNCLAENIYPEV…
A0A835HIC8 31-202 None
A0A0D2MLB6 12-137 None
A0A0G4NA49 139-331 None
V6T7Y4 28-213 None
A0A7J6S362 87-274 None
A0A819Z0J3 41-204 None
A0A2X0N4K4 86-250 None
A0A2H2JMU3 2-122 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.