DPCstruct | MC22675

Metacluster Properties and Pfam Annotations

Number of structural domains915
Mean domain length (aa)309 ± 62 aa
Standard deviation of domain lengths61.70
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.47
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)13.70
Pfam Score38.00
Assigned Pfam label(s) PF09249- PF20266- CL0511- PF20965- PF10421

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A068WA28 146-494 None
A0A414ZVQ1 12-253 None
A0A813Q8U2 230-512 None
A0A075ASG9 16-306 None
A0A8B6FIX1 222-576 None
A0A8B6FL93 2-352 None
R7YRW6 308-649 None
X6N0Z5 68-508 None
K1R4B5 170-574 None
A0A1U7LKP7 8-303 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.