DPCstruct | MC22675

Metacluster Properties and Pfam Annotations

Number of structural domains915
Mean domain length (aa)309 ± 62 aa
Standard deviation of domain lengths61.70
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.47
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.44
Mean intra-cluster sequence similarity (%)13.70
Pfam Score38.00
Assigned Pfam label(s) PF09249- PF20266- CL0511- PF20965- PF10421

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A317J1L7 7-177 KVQASQALRALQIFESLSRYRPTFVGSTPIDLDLNESDLDVICEAYDLDEFEQHAKFVYGNRSNFTCIKVVKYSLPSILVSFFSHNF…
A0A7S1L4K3 95-404 SNEAIQKIELTDQVYGGVHSRLGQGSTLQAVVQRLMAVCKQIEKASFLALEEVVLGGAAGKGLLAAPPQPQAEIVLFVRQLPSRNFA…
A0A6I9K717 10-339 None
A0A1I8IQQ8 675-1018 None
A0A1I8I251 11-228 None
A0A0K0EE34 183-496 None
A0A4S4D7A7 30-381 None
A0A6I8PAE2 554-920 None
A0A7R9NW40 98-397 None
A0A7M5X7R9 161-542 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.