DPCstruct | MC22666

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)66 ± 4 aa
Standard deviation of domain lengths3.86
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score87.05
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)39.13
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U2C2B0 1-64 MWISTDWKDYELLDCGGGERLERWGKYLLVRPDPQAIWRPEGRHPGWRRHDARYQRSSTGGGQW
A0A843EFA2 1-69 MELINNFDDYEIIDASNGEKLERWGNIYLLRPDPQIIWNTGDLREIYKDKIHAVYHRSNKGGGHWEELK
Q8YET1 85-146 None
M3GYS7 507-574 None
A0A7V4HVL0 152-213 None
R5N738 1-65 None
D9MX67 1-63 None
D4IZH9 1-66 None
A0A1Q9AEM9 133-192 None
M3GE47 282-353 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.