DPCstruct | MC22662

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)136 ± 11 aa
Standard deviation of domain lengths10.85
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score84.60
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)30.79
Pfam Score96.43
Assigned Pfam label(s) CL0750- CL0213

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J8E232 15-144 NICTGLWCSTGGSSLSLVIPADGTTCGNNMWCAGYSCVNDLLAPSVTERCMFGDTPFTPINGESCESYIKSQPWQCYVEDNFNKCCQ…
A0A8B6GYQ8 2-134 CGLMWCRDITTQGCKSMVPADGTLCDSKHWCINGVCTYSSGAASTPAKCAHGDYVGSMDNRGNTCTQIVSKDKTECYRDRIGQSCCA…
R7TLI1 545-684 None
T1ETK8 231-368 None
A0A2C9KE57 1-141 None
T1FHV2 246-383 None
A0A812BK71 376-508 None
V4AHG6 453-580 None
T1FWF5 233-383 None
T1FWF6 8-143 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.