DPCstruct | MC22656

Metacluster Properties and Pfam Annotations

Number of structural domains92
Mean domain length (aa)422 ± 101 aa
Standard deviation of domain lengths100.68
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score80.61
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)23.51
Pfam Score94.15
Assigned Pfam label(s) CL0023- PF12777- CL0671

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P4YDA3 2-381 ADKDENLKVRVANLIDAITYAVFIYTSRGLFERDKLIFTSQVAFLVLLMKKEINPTELDFLLRFPARPNCKSPVDFLNDLSWGGIKA…
A0A8B6GF01 25-522 SLVIKLGDAIIPYHHDFKFYITTKMPNPHYTPEVSTKVTLVNFTLSPSGLEDQMLGIVVAEERPDLEEAKNQLIVSNAKMKQELKEI…
A0A0D8XQC7 619-926 None
A0A183WFF4 32-363 None
A0A2P8YMB4 657-1172 None
A0A3P8DWB3 1-458 None
A0A2K1INX7 586-1054 None
A0A7S3G673 2-529 None
A0A4Z2EPQ9 575-1045 None
A0A812JA43 2-348 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.