DPCstruct | MC22628

Metacluster Properties and Pfam Annotations

Number of structural domains112
Mean domain length (aa)153 ± 26 aa
Standard deviation of domain lengths26.08
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score88.40
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)26.15
Pfam Score98.78
Assigned Pfam label(s) PF02615- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K7GUQ9 244-402 None
A0A2S3U3V8 30-157 None
A0A7R8Z8M9 26-243 None
A0A812V5G8 697-870 None
A0A482VS32 192-385 None
A0A3P8KFV9 19-201 None
A0A4Q4ZRK1 170-338 None
A0A0S7DU61 445-605 None
A0A645HQY0 1-116 None
H3AK15 1-126 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.