DPCstruct | MC22625

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)179 ± 31 aa
Standard deviation of domain lengths30.77
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.48
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)31.92
Pfam Score100.00
Assigned Pfam label(s) CL0572

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A661T8L9 1-175 MAVVGAGHEPGIRRYINDDIDIKALETLPPKGKFSGVLKWLIPAVIVCLIIFGFFQGGVDAGKDMIVWWVAVNGIFAGIGAIIAFGH…
A0A7V5ANX2 45-219 KIVAVIGAGHVPGVIENLGRTIDIEPLLTVPPVSPWFKMVGWLLPLFIIGLFVAGFSLSGLKTGMDMLLKWAAVTASFSGLGALLLL…
A0A1V5L4I4 299-481 None
A0A7J3THP3 16-193 None
V7ZP61 80-291 None
A0A6A9SZ76 2-228 None
A0A2M8BK03 486-697 None
A0A1V5XX19 2-113 None
A0A2N1TN23 185-393 None
A0A7X7P5X3 151-330 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.