DPCstruct | MC22623

Metacluster Properties and Pfam Annotations

Number of structural domains74
Mean domain length (aa)131 ± 14 aa
Standard deviation of domain lengths13.57
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score85.08
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)13.92
Pfam Score92.86
Assigned Pfam label(s) CL0172- PF02556

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A661SVK1 57-191 PKFYEAGHDPMHLKSVNVAELFVKVNEIPDDPAKIVHQEMNIFHAHSGYDQERRTIRVGLLLESGMEKERKTAYSMRIELFGEFEAD…
A1WBJ0 8-136 FQIQRVYLKDLSLEQPNSPAILLEQEQPSVDIQLGVEATPVVEGIFEVAVTATVQTKIKDKTVFLVEAKQAGIFEIRNVPEDQMGAI…
A0A7J4JB08 3-137 None
A0A1V5ZGN1 3-147 None
A0A399EW41 53-176 None
C9RG68 17-124 None
A0A3P3XGZ0 3-124 None
A0A4R5MCG4 3-163 None
A0A256ZUQ3 1-112 None
A0A511Z6D2 3-133 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.