DPCstruct | MC22622

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)226 ± 35 aa
Standard deviation of domain lengths34.98
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score82.67
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)20.98
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V8KHD7 4-208 VVLDAETGRQVSVPLGSHHAWTDLEYEKCRHCPLKREEHPECPAAKNLAFVVDDFQLEQSFEKVLVEVVTAERTYRKEVPIQDGLFS…
W9TXA6 2-203 AIEYRITLDDEHDFSYRIELDRGYDAETAAQAPKWTRLEHQRCSNCPLSKDDFSHCPAAVDLHRVIEDFQGLPAIQKALVWVRTPER…
A0A7C9IMG2 2-207 None
A0A1F9RRR8 1-291 None
G7Q938 2-231 None
A0A1G1C1G3 11-198 None
A0A1F9AEI4 18-220 None
A0A1G0ZUM0 18-239 None
A0A2E7IIX8 2-285 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.