DPCstruct | MC22618

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)128 ± 6 aa
Standard deviation of domain lengths6.16
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score88.41
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)38.17
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P7EYC2 132-252 KDILGSFQECQNHLRRYGNVNLELVTRIIRDGGPWEDPVLQAVLKAQPASQEIVNKYLSSENPLFFELRARYLIACERIPEAMALIK…
A0A4Z2IRK0 1-137 MPQHVPVALWEEFQSSTKLAHSLLQESGSTQLCLLSVLAQQDGVWSNNTLSAIMSNQTPQTEQVHEYLELEGATLLNMRIKHLIKME…
A0A4W5PPS6 111-243 None
A0A151PG42 104-232 None
A0A1S3SMP5 64-191 None
D3ZJX1 113-241 None
H2S409 133-256 None
A0A4W5M429 3-134 None
Q9Z2U2 115-247 None
A0A3S2NV83 138-252 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.