DPCstruct | MC22614

Metacluster Properties and Pfam Annotations

Number of structural domains525
Mean domain length (aa)124 ± 17 aa
Standard deviation of domain lengths16.64
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score71.95
Mean fraction of residues predicted as intrinsically disordered0.75
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)31.57
Pfam Score99.72
Assigned Pfam label(s) PF07217- CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z5X6L4 157-279 None
A0A4Z0PNS8 84-212 None
A0A6V6YJ69 172-297 None
H6RPH6 7-136 None
A0A484HJL7 84-203 None
A0A7C3GQZ4 70-200 None
A0A2T4V8H5 129-260 None
A0A160TLX0 282-405 None
A0A1I0BXF1 137-287 None
A0A1H8DCB4 101-199 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.