DPCstruct | MC22614

Metacluster Properties and Pfam Annotations

Number of structural domains525
Mean domain length (aa)124 ± 17 aa
Standard deviation of domain lengths16.64
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score71.95
Mean fraction of residues predicted as intrinsically disordered0.75
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)31.57
Pfam Score99.72
Assigned Pfam label(s) PF07217- CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A533ISX9 24-166 RPLTPGEAKRVAAAFGEELPARALRFVPGPGRSAFAAMAFRKGNPAITVGRTVYIRADRYRPDLAATPEDIELLVHECTHVVQYRRH…
A0A5B8U5V6 16-124 DVQAAIGLAHGGGRPLHEGTAGRLSEVLQDPLHDVRVHDGPEAAMLARAVAARAFTVGNDIFFGAGEYRPGTADGDRLIAHEATHVI…
A0A2T6CHJ5 5-118 None
A0A833GXS7 195-309 None
A0A833M0K9 73-205 None
A0A7U4P9K8 90-236 None
A0A833GXN6 110-228 None
A0A2T4ZVB9 105-231 None
A0A840KBA9 95-212 None
A0A7K3G854 87-227 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.