DPCstruct | MC22610

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)95 ± 12 aa
Standard deviation of domain lengths11.92
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score90.95
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)36.36
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S6B649 3-82 HETEIDIRALFPGQLIVHNVAREDIREGVSITDPDIILEVEDRTISVYMRAFIPTKVLQVPGNPYSGHRAELVRVWSEMY
A0A837B5K9 21-125 PSTVDIDWTAMDGVERYTEIDFEKIFPGHVILHSVAREDVDEFFLLHGYFADGRHHVYILLEVNDRTINVYMRSRILTKYLVDPEHD…
A0A3M2HEU8 1-93 None
A0A0G9HE41 185-282 None
A0A4P5SJ25 74-183 None
A0A3M2HJQ0 83-182 None
A0A3S9NFS8 28-139 None
A0A0Q9EPR1 6-104 None
A0A836P243 1-67 None
A0A4R0YSX1 125-221 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.