DPCstruct | MC22605

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)289 ± 36 aa
Standard deviation of domain lengths36.35
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score67.25
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)37.87
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q84TJ4 123-435 LVESGSQWDEFIRLLCECLRLAVIYSFPIPAVGSETGFGSLDQCFFGSDVLKCKLEKANWSTVSDIFRVLRNILKRLSQEDNEEIFD…
A0A540N7L0 1-308 MCSDSKLSRLCRLDDDFLRPYTFYVFFRGSNWEGFICLLCVCMNLAITVAVSCSSSCSVDGADDLHSGSSRLILVLKPKLENADWSI…
A0A1D6QUU4 12-282 None
A0A833V4T5 94-358 None
A0A1I9LSE6 123-435 None
A0A453BPB9 9-281 None
A0A453BP84 1-284 None
A0A453BP17 1-295 None
A0A1D6QUU7 125-412 None
A0A1D6QUS9 104-327 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.