DPCstruct | MC22604

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)112 ± 13 aa
Standard deviation of domain lengths12.81
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score79.39
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)61.83
Pfam Score100.00
Assigned Pfam label(s) CL0154

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A540N1L9 3-103 YKQAPRELLQLMPPLNPMPSQQRYLQYITRRNVGSEWPPLDRALTLDCIIIRFIPNMDREGGCRPIFRIYGQDPFMAADRTPKVLFS…
A0A251UKW5 134-257 AFMVAAHTLYRQNFTVETKALDTVYKRASNDLLPGMSPLNPVPSQLRYLQYISRRNADSEWPPADKALTLDCVIMRTIPDFDGKGGC…
A0A6P5XNN5 135-258 None
M7YNU1 128-219 None
A0A5J5V166 136-258 None
A0A2K3NF85 1-90 None
C7J5K4 135-257 None
A0A453PW84 26-126 None
A0A1D6HBS1 100-200 None
A0A2P2K1Q4 2-120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.