DPCstruct | MC22595

Metacluster Properties and Pfam Annotations

Number of structural domains443
Mean domain length (aa)123 ± 25 aa
Standard deviation of domain lengths25.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.76
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)23.63
Pfam Score98.44
Assigned Pfam label(s) PF04885- CL0159- CL0005- PF00086- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R8W8I2 522-645 None
A0A7R8W033 470-574 None
A0A2H1V7U2 16-121 None
D8U3P2 712-830 None
A0A671WR66 258-409 None
A0A6F9B0N0 531-698 None
A0A6P8XMW5 69-197 None
G5C5W7 203-341 None
B3S9W4 779-887 None
Z4YJS5 388-495 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.