DPCstruct | MC22595

Metacluster Properties and Pfam Annotations

Number of structural domains443
Mean domain length (aa)123 ± 25 aa
Standard deviation of domain lengths25.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.76
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)23.63
Pfam Score98.44
Assigned Pfam label(s) PF04885- CL0159- CL0005- PF00086- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0R3VUR8 56-210 None
A0A3S2TN52 10-140 None
A0A7V6E8A0 531-655 None
A0A2D4BUJ5 265-376 None
A0A1I8PHS1 5-160 None
A0A1V9XAJ3 58-141 None
A0A6F9BYQ9 64-212 None
A0A6P2ASU2 164-286 None
A0A835Z4F2 8-86 None
A0A7M7SSS0 18-198 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.