DPCstruct | MC22595

Metacluster Properties and Pfam Annotations

Number of structural domains443
Mean domain length (aa)123 ± 25 aa
Standard deviation of domain lengths25.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.76
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)23.63
Pfam Score98.44
Assigned Pfam label(s) PF04885- CL0159- CL0005- PF00086- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y2C3A2 9-100 None
A0A814GBH4 66-207 None
A0A388M1T9 287-385 None
A0A2E4EE46 20-132 None
A0A6J2ST76 64-202 None
A0A6J1M9Z6 2-147 None
A0A1L8DP53 38-190 None
A0A7F5R4A9 373-509 None
A0A2H9T0Y5 130-225 None
A0A7S3XIM7 8-139 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.