DPCstruct | MC22595

Metacluster Properties and Pfam Annotations

Number of structural domains443
Mean domain length (aa)123 ± 25 aa
Standard deviation of domain lengths25.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.76
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)23.63
Pfam Score98.44
Assigned Pfam label(s) PF04885- CL0159- CL0005- PF00086- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H2IAW8 193-331 None
A0A356T721 195-341 None
A0A356T1V8 20-108 None
A0A044RLZ9 328-455 None
A0A2T7P6P9 16-100 None
F0WP03 202-323 None
F0WEP6 4-104 None
F0WEQ0 6-143 None
A0A7R8HC84 1-117 None
A0A7S1KTD7 153-281 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.