DPCstruct | MC22595

Metacluster Properties and Pfam Annotations

Number of structural domains443
Mean domain length (aa)123 ± 25 aa
Standard deviation of domain lengths25.41
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.76
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)23.63
Pfam Score98.44
Assigned Pfam label(s) PF04885- CL0159- CL0005- PF00086- CL0001

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C5MF94 123-251 FWCLFETGACAGPGTCKEVPKVCTSVLQPVCGCDGKTYNNPCLAAVARVNIKSPGACPGGPCTSNLDCAPKEYCKKDIGDCQGKGQC…
A0A225US26 6-120 YKGGDCDDQGCPDQYAPVCGSDGVTYSNECNLSIEKCNHPEKNLTMVLDGECPTQRKLMFSEGYQGGDCEDQGCPDDYAPVCGSDGV…
A0A6S7GHN6 72-188 None
A0A2Z4FK43 142-228 None
A0A1D2NDM7 209-324 None
P86987 6-179 None
A0A7C5J4Q5 4-124 None
A0A1G2VKT4 779-884 None
A0A7R9KCA8 353-426 None
A0A7R9KNR3 68-228 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.