DPCstruct | MC22594

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)129 ± 20 aa
Standard deviation of domain lengths19.85
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score75.68
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)31.32
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M4BQ75 95-251 HQRLTRVVHLWTGSSRWRPTRKALIKIITRRLHFQGLRHRDQRETRPDFRVVSAGTDLVEWKELRHVRETFPTGVQTLYRLKSNSFP…
A0A225ULF0 10-122 YQHPHPLLSRLVCLWVGKRRWTQKRAHFKRAIAKASKQRGFTAKAERENNWRVTGGSIGAIISGLEWKRLRRILGLNAWGEQLLFRI…
A0A6A3UAI9 101-209 None
A0A225WDP5 1-141 None
A0A225WY02 63-178 None
D0NDX0 57-196 None
A0A225W6M8 8-111 None
A0A6A3RWY5 84-175 None
A0A225WCQ2 488-640 None
M4BC18 29-183 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.