DPCstruct | MC22582

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)283 ± 44 aa
Standard deviation of domain lengths44.01
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.93
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)39.26
Pfam Score75.48
Assigned Pfam label(s) CL0264- CL0125- CL0707

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812D175 2-228 SKAAERFCSFLPNDMLAKFCKDQVQKFVPWLNNMHFLGATPDLICQTLHFCTNKKGKFCYLFPQKTLKNYYKHLPKYDKDGDLYSQN…
A0A6J0AGN5 2-277 ERLCSYMPEKLFLKTTCYLVVHIFGPDIIKLLSADMNADVVCHTLEFCKQDPGQPFCHLYPLPKEPWKFTLETARQIVKKSPTLTYS…
A0A817E5K0 1-327 None
A0A2T7NHC7 3-326 None
A0A812WFF9 117-375 None
A0A7R8ZEN9 1-279 None
A0A7M4EVF7 11-281 None
V4BLT0 58-339 None
A0A820A6N4 56-323 None
A0A819H1X5 396-715 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.