DPCstruct | MC2257

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)121 ± 16 aa
Standard deviation of domain lengths16.29
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.38
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)21.44
Pfam Score100.00
Assigned Pfam label(s) PF14129

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A521BGE2 4-104 LWACKNNKIPADIIPKEKMILMMIDMHYADAYFNREIESDSTLARTNALYKFIFKKYKTDSVQFKHSFDYYAENPEILDNIYEAMID…
W6TNS5 6-125 YTAFLFLFVAGCKPGIPSDIIQPDKMALVLHDIHIVDAYITTIPNIDTSRTMAAAYYSGIYKRYEIDSALYGKSMAYYSQHPKVLDG…
A0A2P6BZ95 9-110 None
A0A660YA12 12-140 None
A0A1Y2REX0 2-103 None
A0A1F3QSI5 1-88 None
A0A2S5A2R8 23-153 None
A0A173MM98 1-152 None
A0A2S1LMV9 7-160 None
A0A2N2WES4 57-175 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.