DPCstruct | MC22568

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)226 ± 36 aa
Standard deviation of domain lengths35.96
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score78.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)23.70
Pfam Score91.67
Assigned Pfam label(s) CL0020- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812EDZ6 687-900 KSEKTAVNWQGLEASETRAKYLYRSEERFHALQMCGWGNLQDPNGLNKLLEKLQSEGEYERAAAIALFNLQIKRSLAILNTPRNADS…
A0A1R2CVV2 76-246 GIGEILEESKSTQKSKGTFTQYSSSERSKCLMFLGWPETPKSLGPITKKLVEDGQFERAAFISVAFGEYQRAVEALKAKKNEHQILY…
A0A819AWN6 871-1066 None
A0A7M3R0L9 2-291 None
M5BT67 543-805 None
A0A5B7EM90 192-393 None
A0A183CKT9 206-434 None
A0A7S4RBD2 287-527 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.