DPCstruct | MC22559

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)388 ± 44 aa
Standard deviation of domain lengths43.55
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score73.89
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)21.61
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5E4N201 23-404 VSGARVGPPVNVGTVLYGKRDLAKYWTDREAAGLRCREMADQLIPRRIPDGAAFVDYFKLIEVQSSLTVDSQTSRRRIMSAVADAVG…
A0A6J1NJ55 21-402 ASPNVGTVLYSAADLKKTQWSKTDIALLQARKYLQNVIPSSRLESTIDEEYLRNLLTYFENCYSTVKREINDPTLRNLMNVALSDAL…
A0A482VVB1 3-410 None
A0A4C1TWU4 12-452 None
T1HMF3 38-421 None
B3LXM8 122-527 None
A0A1B6JVD7 20-374 None
A0A6P7FAG5 2-344 None
A0A5E4MF18 18-362 None
A0A0L0C7J0 231-677 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.