DPCstruct | MC22553

Metacluster Properties and Pfam Annotations

Number of structural domains67
Mean domain length (aa)356 ± 72 aa
Standard deviation of domain lengths72.25
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score83.45
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)19.28
Pfam Score95.83
Assigned Pfam label(s) CL0154- CL0072- CL0105- CL0366- CL0016

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0A8L311 23-236 ARNFQFINSKVRTLPMLADVVVPMRLEPVPVDALWGEVLQEENISIDDSYVECIKMPLLHAGDSTCEELDHFNRIYQCATRNAVTWE…
A0A6P6DU82 22-419 RVAPNSCPRVLTREPPGPRRGMEEEKMDENEWGYHGEGNKSLVVAHAQRCVVLRFLKFPPNRKKTSEEILQHLQDIVDFGKNVMKEF…
A0A0C2JYE7 10-365 None
A0A1A8H8D5 11-339 None
A0A146HPD4 2-271 None
A0A812IZS4 293-653 None
A0A164YC08 188-645 None
A0A6G1IGQ1 40-404 None
A0A1Q5SUA0 10-284 None
A0A1J8QA36 10-412 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.