DPCstruct | MC22548

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)442 ± 75 aa
Standard deviation of domain lengths74.55
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score76.05
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)23.84
Pfam Score81.62
Assigned Pfam label(s) CL0260- CL0237- CL0220- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7U6QPV2 2-330 STLDAVRPEKQRTTAQETLDFYVPFARLMGLNDIADYIEVLCYRNLDSDMYNKISDKLLQHGLGRNFQREAIHRYLSIVLNNLGLNG…
A0A3D0LHA6 12-484 SAEKRYVELIKKIRTYMTADTSLLRDAYDTAMEKHKCSRRKGGAPYITHPLEVAHFCADMKRDNEVIAAALLHDVVEDEDITMTEIG…
A2Y0P1 50-468 None
A0A287HKV6 3-369 None
A0A2P2MT22 6-457 None
I4I5X5 189-551 None
A0A838RH61 2-474 None
A0A2R7S737 4-368 None
A3BZA4 618-1064 None
A0A484Y2R8 7-355 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.