DPCstruct | MC22508

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)149 ± 23 aa
Standard deviation of domain lengths22.77
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score77.01
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)34.20
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A518D754 511-626 LREWAGPNSAGRCATCHSLQRQGDHLAFGWRPHDRTTEARGFTRFSHRPHLVQPELRDCRHCHQIDTGAEVSASYASLDPAVFVSEF…
A0A7Z9K2Y8 13-160 EGNNKVEPGWATDIFEELANAKGPGVCIKCHSIDQSDNANVSINWRGARPDPNQHSFTKYSHESHFSLLDEKGCVTCHIVNKESDFS…
A0A3D1XQA9 242-428 None
A0A7T7YEL1 682-809 None
A0A7V2AM72 223-349 None
A0A1Z7Z6R0 267-398 None
A0A2E4UPC7 213-384 None
A0A836QRR9 442-632 None
A0A7Z9FCP8 128-287 None
A0A2D8PQF7 318-496 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.