DPCstruct | MC22491

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)131 ± 16 aa
Standard deviation of domain lengths15.96
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score82.52
Mean fraction of residues predicted as intrinsically disordered0.14
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)61.20
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D0QI38 158-294 SIQFLLNLSIAAVDCKSDKGESFTELLASACSYNTFPFGEEYGFQEEQSDFLLDLYSRVKQYESETGRRVLPALLPVYQSVPAVWSI…
A0A7J6DBM3 1-133 MFPSHSSHPYCQLVETDKDAGTRFLTQLSSVCSYKTFPFNYNRHDQSDFLLDLCSHVKYYETQTGRSYLPALQSVFQSPDVWIIDLS…
A0A6A5F286 4-158 None
A0A1S3Q421 286-396 None
A0A674DG97 935-1069 None
A0A7J6ACW6 394-531 None
A0A3B3QBS2 380-520 None
A0A2I4AM06 2-156 None
A0A498P1Y9 274-404 None
A0A5N5JI95 3-96 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.