DPCstruct | MC22488

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)101 ± 13 aa
Standard deviation of domain lengths13.46
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score90.37
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)35.59
Pfam Score100.00
Assigned Pfam label(s) CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q2LRH6 256-357 TGKPISQGGIHGRISATGRGLFHGIENFINEASYMSILGMTPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDG…
S3HJW6 1-84 MGNFTSALLRKFHPALTQAGLRRVVPIEGARVAVQGFGNVGGIAARLFEQAGARIVALQDHSATLVDEAGINVLAAGEHVGRTG
A0A812QV07 809-933 None
A0A4Y1R263 96-191 None
A0A380DP07 213-296 None
R9A988 366-461 None
L9KGD0 23-124 None
A0A101RM06 60-136 None
A0A0G1R9L8 174-257 None
A0A101ER55 144-229 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.