DPCstruct | MC22480

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)82 ± 17 aa
Standard deviation of domain lengths17.49
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score68.75
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)52.02
Pfam Score100.00
Assigned Pfam label(s) PF00428

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I7XQ74 1-85 MKYLGAYLLANLGGNDSPSAQDILKILGAGGLDCDMEDATKVVESLSGKNISEVITEGKKKLSSVPSGGSPSGSAAPVAASTAPK
A0A660KQQ2 1-52 MKVVAAYLLAVLGGNTSPSAEDVKNILGSVGAEADEDRIELFLCEVKGYGLQ
A0A445IJ59 136-239 None
A0A3Q7E9G4 884-934 None
I7J968 2-108 None
A0A6G1DUB7 23-83 None
A0A3N4JVF8 1-100 None
A0A0A9EQA2 1-47 None
A0A7J0GHS0 1-86 None
A0A803JQS2 1-89 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.