DPCstruct | MC22470

Metacluster Properties and Pfam Annotations

Number of structural domains79
Mean domain length (aa)155 ± 39 aa
Standard deviation of domain lengths39.23
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score74.38
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)34.57
Pfam Score89.47
Assigned Pfam label(s) CL0220- CL0066

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G3Q455 1-87 MTPQNFIESVTMSEPRNKRPWRSLAKQELEKILSETPLVWRGSSKLFRNLRERGIISYTEYLFLLCILTKPHAGFKIAFNMFDADGN
A0A1I7XBB4 28-164 YLNFEEENKTKDQIHTKHKLTKRELRFIQFASIEYNDVIYMSPMDFIDSLTLDCPRERVYRRVLNDKDLKQILYRTPPFRCGSKDLF…
A0A7M7IJF3 591-724 None
A0A0X3NJ32 26-184 None
A0A835Q2C3 13-144 None
A0A7J7Z693 1-132 None
A0A6V7Y5J0 822-1059 None
A0A6J2AXU3 139-272 None
A0A6V7VS87 40-234 None
L8H3D2 1-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.